Buy Zyrtec Online
from $1.08 per pill
One of the reliable second-generation drugs antihistamines is Cetirizine. The list of useful properties of this medication and drops include antipruritic and antiexudative action. Especially often this medication is given to fight the skin manifestations of allergy.
Before use Cetirizine, please consider the following information.
The active ingredient of Zyrtec is Cetirizine dihydrochloride. This is a competitive inhibitor of histamine, which reliably blocks histamine receptors. Because of this medication not only makes the patient feel better, but also prevents the development of allergy, and has antipruritic effect. Cetirizine has effect on early and a late stage of allergic reaction, stabilizing membranes and preventing the migration of basophils, neutrophils and eosinophils. This reduces the permeability of skin capillaries, the severity of smooth muscle spasm. Cetirizine is able to eliminate the cutaneous manifestations of hypersensitivity reactions in response to specific allergens, as well as exposure to cold in the case of cold urticaria. The advantages of Cetirizine should include almost complete absence of sedative and anticholinergic effects when taken in therapeutic doses. After rapid absorption when administered Cetirizine creates maximum serum concentration already after 1 hour after intake. Presence of food in the stomach during the use of the drug has no effect on the completeness of absorption, but lengthens this process for 1 hour. Up to 93 % of the drug is bound to plasma proteins, which is responsible for its high bioavailability. The active drug substance is metabolized in the liver. With prolonged use Cetirizine not cumulate in the body. More than 2/3 of the drug is excreted by the kidneys. The half-life is from 7 to 10 hours, decreasing in children and increasing the elderly.
Cetirizine is indicated for the following diseases: year-round and seasonal form of allergic rhinitis, hay fever, chronic idiopathic urticaria; angioedema, atopic dermatitis, allergic dermatitis, etc. One can use Cetirizine hydrochloride, but it is recommended to consult your physician first.
Cetirizine is not recommended for use during pregnancy, lactation, hypersensitivity to the presence of components of the medication. With extreme caution Cetirizine is indicated for people with renal failure and for the elderly.
Adults are recommended to take 10 mg of Cetirizine (20 drops or 1 tablet) 1 time per day. With decreasing clearance of creatinine it is required to reduce the dosage of the medication.
Cetirizine: Side effects
Before use Cetirizine hydrochloride 10mg, you should know that side effects include: drowsiness, headache, dry mouth. More rarely one might experience migraine, headache, dizziness and allergic reactions (hives, rash, itching, swelling).
If you are receiving a dose of Cetirizine more than 50 mg overdose symptoms might take place: irritability, drowsiness, restlessness, urinary retention, constipation, dry mouth, tachycardia. In this case, we recommend the implementation of measures aimed at evacuating the drug from the gastrointestinal tract, and immediate medical help.
When using Cetirizine with other medications, such as cimetidine, ketoconazole, erythromycin, diazepam, azithromycin, glipizide there were no significant clinical or pharmacokinetic interactions. When the medication was used simultaneously with theophylline there was a decrease in creatinine clearance. The simultaneous use of macrolides does not cause changes in the ECG.
If you are looking where to get Cetirizine, you should first consider the information below.
The components of the drug can penetrate through placental barrier, so it is not prescribed to pregnant women. During lactation period the reception of Cetirizine requires temporary cessation of breastfeeding.
For the children from 6 months to 6 years the medication is prescribed as drops. Children from 6 to 12 months are prescribed 2.5 mg of the medication. Children from 1 to 2 years are prescribed 5-5 mg of Cetirizine. Children from 2 to 6 years are recommended to take 5 mg of Cetirizine. Children from 6 are prescribed the same dosage as adults. The potential risk of sudden infant death syndrome requires special care in these situations: the presence of sleep apnea syndrome, the presence of sleep apnea or sudden deaths in other children in the family, co-administration with drugs that have a depressing effect on the central nervous system, treatment of premature born baby. The analogs of Cetirizine containing Cetirizine hydrochloride, are drugs such as Alerza, Tsetirinaks, Parlazin, Cetirizine hexane Zodak, Letizen, Zetrinal, Allertek, Zintset. Despite the fact that the use of Cetirizine 10 mg does not lead to a quantitative decrease in the ability to operate machinery or driving a car, in these situations one should be careful. Overall, the medication can be a reliable tool for solving problems of allergies in children and adults.